TTFB shows how quickly the server starts answering, before anything is downloaded or rendered. A high TTFB delays everything after it, including Largest Contentful Paint.
Google’s guidance is a TTFB of 0.8 seconds or less at the 75th percentile of visits. The usual causes of a slow one are pages built from scratch on every request, slow database queries, cold starts, redirects and long distances to the server; page caching and a CDN usually help most.
Tools measure it differently. Browsers count from the start of navigation, including redirects, DNS, connect and TLS; some monitoring tools report only the server’s wait after the request was sent. Compare numbers from the same tool.